25 May 2022

Genetic study of childhood anxiety and depression

A genome-wide association study of childhood internalising symptoms by the EAGLE consortium was recently published in the Journal of the American Academy of Child and Adolescent Psychiatry (JAACAP). The study sheds light on the genetic architecture of early symptoms of depression and anxiety and reveals genetic overlap between childhood and adult mental health disorders. Christel Middeldorp, professor of Child & Youth Psychiatry at the University of Queensland said, “These findings are important because they help identify people most at risk of symptoms continuing across the lifespan, so intense treatment can be provided where needed.” Professor Middeldorp further highlights the results of this work in a press release published by the University of Queensland.

17 August 2021

Genomics of human aggression

The EAGLE “Genetic association study of childhood aggression across raters, instruments, and age” has now been accepted in Translational Psychiatry!
The study of “Continuity of Genetic Risk for Aggressive Behavior Across the Life-Course” has now been published in Behavior Genetics (doi: 10.1007/s10519-021-10076-6) and describes a successful application in Dutch and Australian cohorts of the PGS for aggression across the life span. Watch the space!